Symbol
Name
ID

Abcb4
ATP-binding cassette, sub-family B member 4
MGI:97569

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgA level	Increased circulating IgM level	Splenomegaly
Disease(s) Associated with ABCB4	Increased circulating IgA level	Increased circulating IgM level	Splenomegaly
primary biliary cholangitis
progressive familial intrahepatic cholestasis 3

Mouse Phenotypes

enlarged spleen

increased spleen weight

increased basophil cell number

decreased hemoglobin content

decreased mean corpuscular hemoglobin

decreased mean corpuscular hemoglobin concentration

decreased mean corpuscular volume

increased red blood cell distribution width

increased neutrophil cell number

thrombocytosis

increased lymphocyte cell number

increased monocyte cell number

increased leukocyte cell number

Availability

Mouse Genotype

Abcb4^em1(IMPC)H/Abcb4^em1(IMPC)H

Abcb4^tm1Bor/Abcb4^tm1Bor

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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